A highlight from the LUPUS 2014 meeting: eight great ideas

نویسندگان

  • Jill P Buyon
  • Phillip Cohen
  • Joan T Merrill
  • Gary Gilkeson
  • Mariana Kaplan
  • Judith James
  • W Joseph McCune
  • Sasha Bernatsky
  • Keith Elkon
چکیده

This review describes eight 'great ideas' regarding bench-to-bedside considerations in systemic lupus erythematosus (SLE) presented at the second international LUPUS meeting in Quebec, September 2014. The topics included: correcting the impaired clearance of apoptotic fragments; optimisation of clinical trial design: the PERFECT (Pre Evaluation Reducing Frighteningly Elevated Coverable Targets) study; lipidomics and metabolomics in SLE; importance of the inflammasome; identification and treatment of asymptomatic autoimmunity: prevention of SLE; combining low doses of hydroxychloroquine and quinacrine for long-term maintenance therapy of SLE; reducing emergency room visits and the critical relevance of the autoantigen.

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عنوان ژورنال:

دوره 2  شماره 

صفحات  -

تاریخ انتشار 2015